Day 1 (October 25^th,   2019, Friday), Science and Technology Park, Hangzhou Normal University

08:00-20:00

All

Registration

13:00-14:00

Members   of Biophysics Society of Zhejiang,

Annual business meeting of Biophysics   Society of Zhejiang (Building D, Room 618)

13:00-14:00

Members   of CEPP Editorial Board

Editorial Board Meeting (Building D, Room 617)

14:00-17:20

Chaired   by: Junping Liu

Session   1: Research directions in gerontology for considerations of the State Fourteenth   Five-Year Plan (Building E, 3rd floor, Conference Room)

14:00-14:10

Zhijun   Bao/Chao Zhao

Ageing injury of hepatointestinal epithelium

14:10-14:20

Guangyan   Cai

Renal tubular epithelial senescence and renal failure

14:20-14:30

Biao   Chen

Frailty: current status and future strategies

14:30-14:40

Baohua   Liu

Chromosomal homeostasis and ageing related diseases

14:40-14:50

Guanghui   Liu

Gene editing in ageing related diseases

14:50-15:00

Junping   Liu

Research Progress of Parkinson’s Disease

15:00-15:10

Qiang   Liu

Mechanisms of RNA homeostasis in ageing-related diseases

15:10-15:20

Moshi   Song

Mitochondrial metabolism in ageing

线粒体代谢问题在衰老中作用的研究进展

Research progress on the role of mitochondrial metabolism   in aging

15:20-15:30

Jiacan   Su/Li Su

Bone and joint ageing and diseases

15:30-15:40

Lihui   Wang

Mechanisms and molecular targets of cellular senescence in   COPD

慢阻肺的细胞衰老机制与分子靶点

Mechanisms and molecular targets of cellular senescence in   chronic obstructive pulmonary disease

慢阻肺的细胞衰老机制与分子靶点

Mechanisms and molecular targets of cellular senescence in   chronic obstructive pulmonary disease

15:40-15:50

Yanjiang   Wang

Research Progress of Alzheimer’s Disease

15:50-16:00

All

Coffee break

16:00-16:10

Ze   Yang

Longevity genetics

16:10-16:20

Jing   Ye

Advances in telomere, stem cells and ageing related diseases

16:20-16:30

Weiqi   Zhang

Vascular ageing related diseases

16:30-16:40

Haiyun   Chen

1,25(OH)2D in the Prevention of   Mandibular Osteoporosis via the Deacetylase Sirtuin-1

16:40-16:50

Jian   Sima/Li Su

Proteomics-based   target identification and translational study in aging-related diseases

16:50-17:00

Chuanxin   Sun

A Novel   Compound From Lycium barbarum Prevents from Bone Loss In Aging Mice

17:00-17:10

Yiqi   Wan

Genetic contribution to the escape of   centenarians from type-2 diabetes

17:10-17:20

Jiaping Wu

Potentiating   of exercise training with resveratrol during aging cardiac hypertrophy

17:20-17:30

Jingjun   Zhou

Molecular   identities of intracellular calcium overload-induced injury in hearts

17:30-18:30

All

Dinner (B building, First Floor, Bai-Jia-Wang restaurant)   and poster viewing

Day 2 (October 26^th,   2019, Saturday) , Science and Technology Park, Hangzhou Normal University

08:00-08:10

Chaired by: Junping Liu & Yong Shen

Welcome

08:10-08:40

Suzanne Cory

BCL-2: from   translocation to therapy

08:40-09:00

Xinhua Feng

How Cancer Escapes   from TGF-βAnti-growth Signaling

09:00-09:20

Guanghui Liu

Using stem cell and   gene editing to study and treat aging-related disorders

09:20-09:40

Yu Sun

Senescence   associated secretory phenotype (SASP) in therapeutic resistance

09:40-10:00

Zhixiong Xiao

IGF-1 transgenic   mice exhibit aging-like phenotypes via SIRT1 axis

10:00-10:20

Junfeng Ji

CLDN1 as a novel   surface biomarker for targeted elimination of senescent cells

10:20-10:30

All

Coffee break and   poster viewing

10:30-12:40

Chaired by: Baohua Liu & Guanghui Liu

Session 3: Genome programming of   ageing and longevity

(Building   E, 3rd floor, Conference Room)

10:30-11:00

Jan Vilg

Single-cell approaches in   studying genome instability in aging

11:00-11:20

Jingdong Han

Heterogeneity of Human Aging

11:20-11:40

Zhongjun Zhou

Lamin A-SIRT6-p53 axis in lifespan control and aging

11:40-12:00

Zhiyong Mao

A PARP1-BRG1-SIRT1 axis promotes HR   repair at DNA damage sites

12:00-12:20

Xiaoli Tian

Epigenetic control of endothelial cell senescence

12:20-12:40

Wengong Wang

Regulation of liver lipid balance by HuR

12:40-13:30

All

Group photograph and Lunch break (B building, First Floor,   Bai-Jia-Wang restaurant)

13:00-13:30

Hongyu Wang

Workshop: Application   of genetically engineered mice in biomedical research

13:30-16:10

Chaired by: Moshi Song & Weiqi Zhang

Session 4: Hormones, obesity and cardiovascular   diseases 

(Building   E, 3rd floor, Conference Room)

13:30-13:50

John Funder

Adrenal hypertrophy and aldosterone adenoma in the elderly

13:50-14:10

Dengli Hong

Tracking down the Origin of Leukemic Stem Cell Programs in Fetal and   Aging Hematopoiesis Development

14:10-14:30

Wei Li

Autophagy-dependent   and independent functions of Ei24 in the Sertoli cells

14:30-14:50

Baohua Liu

Sirt7 regulates   hepatic circadian phase coherence and gluconeogenesis

14:50-15:10

Helena Qin

Exploring biased   agonism for myocardial infarction

15:10-15:30

Moshi Song

Mitochondrial regulation of cardiac degeneration

15:30-15:50

Weiqi Zhang

A Single-Cell   Transcriptomic Atlas of Arterial Aging in Cynomolgus Monkey

15:50-16:10

Xudong Zhu

Fine-Tuning of PGC1α   Regulates Cardiac Function and Longevity

16:10-16:20

All

Coffee break and poster viewing

16:20-19:00

Chaired by: Qiang Liu & Yong Shen

Session   5: Degenerative diseases: Mechanism and intervention

(Building   E, 3rd floor, Conference Room)

16:20-16:40

Nady Braidy

Promoting   Healthy Ageing: Unravelling the secrets of our cellular ‘energy sensor’ NAD⁺

16:40-17:00

Shiqing Cai

Neural basis   of age-related behavioral deterioration

17:00-17:20

Qiang Liu

Epigenetic   regulation and Alzheimer's disease responses

17:20-17:40

Chao Tong

Mitochondria   and neurodegeneration

17:40-18:00

Lei Liu

Enhancing   glycolysis attenuates Parkinson’s disease progression

18:00-18:20

Yanjiang Wang

From pathogenesis   to therapies for Alzheimer’s disease from systemic approaches

18:20-18:40

Jiawei Zhou

Role of NG2   glia in neuroinflammation: Implication for Parkinson’s disease

18:40-19:00

Xinhua   Zhan

Bacterial   molecules associate with Alzheimer’s Disease neuropathology

19:00-20:30

All

Dinner (B building,   First Floor, Bai-Jia-Wang restaurant) and poster viewing

20:30-21:30

Chinese Society of Ageing Biology

Annual business   meeting of Chinese Society of Ageing Biology (Building D, Room 618)

Day 3 (October 27^th,   2019, Sunday) , Science and Technology Park, Hangzhou Normal University

08:00-10:00

Chaired by: Chang   Chen & Jiacan Su

Session 6:   Metabolic disorders and ageing diseases

(Building   E, 3rd floor, Conference Room)

08:00-08:20

Chang Chen

Redox-stress   Response Resistance (RRR) in Aging

08:20-08:40

Jian Luo

Regulation of body   length and osteoporosis by GPCRs

08:40-09:00

Dengshun Miao

Sirt1   protects against estrogen deficiency-induced osteoporosis

09:00-09:20

Jiacan Su

Central   problems and Countermeasures of osteoporotic fracture

09:20-09:40

Dakang Xu

Targeting inflammaging   and immune checkpoints for reversing immunosenescence

09:40-10:00

Xiaoling Zhang

Steady-state   imbalance and degeneration regulation of joint

10:00-10:10

All

Coffee break and   poster viewing

10:10-12:20

Chaired by: Eric   Gilson & Yong Zhao

Session   7: Telomeres, DNA damage response and disease

(Building   E, 3rd floor, Conference Room)

10:10-10:40

Eric Gilson

TBA

10:40-11:00

Zhenyu Ju

Metabolism,   Inflammation and Ageing

11:00-11:20

Wenbin Ma

Genome-wide screens   of telomerase associated proteins in live cells

11:20-11:40

Yong Zhao

RBMX is Required for   Activation of ATR on Repetitive DNAs to Maintain Genome Stability

11:40-12:00

Jing Ye

TERFA controls   neuronal homeostasis in zebrafishes

by regulating glial   cell functions

12:00-12:20

Yongqun Zhu

Molecular Mechanisms   of Host Subversion by Bacterial Pathogens

12:20-13:00

All

Lunch break (B   building, First Floor, Bai-Jia-Wang restaurant) and poster viewing

13:00-15:10

Chaired by: Yong Shen & Ze Yang

Session   8：Intervention   strategies and methods for ageing-related diseases (Building E, 3rd floor, Conference   Room)

13:00-13:30

Vincent Geli

The p21-mTert   knock-In mouse: a model of senescence bypass in lung disease

13:30-13:50

Jing Qu

Gene therapy   alleviates osteoarthritis by preventing cellular senescence

13:50-14:10

Chris R   Triggle

Concentration-Dependent   effects of metformin on endothelial function

14:10-14:30

Feng Wang

The function   of CST and its partner in resolving telomeric DNA replication problems

14:30-14:50

Ze Yang

Healthy   ageing and longevity

14:50-15:10

Yufeng Zang

Precise localization of abnormal   spontaneous brain activity by resting-state fMRI.

15:10-15:30

All

Student’s Award presentation and   closing (Building E, 3rd floor, Conference Room)

2019年10月25日，星期五，杭州师范大学科技园

08:00-20:00

全体

报到注册

13:00-14:00

浙江省生物物理学会理事

浙江省生物物理学会理事会会议（杭师大科技园D座6楼衰老所D618会议室）

13:00-14:00

CEPP编辑部

CEPP编辑部会议（杭师大科技园D座6楼衰老所D617会议室）

14:00-17:20

主席：刘俊平

主题1：老年医学十四五发展战略研究调研会（杭师大科技园E座3楼报告厅）

报告时间5分钟，讨论5分钟

14:00-14:10

保志军/赵超

肝肠上皮衰老损伤研究的现状

14:10-14:20

蔡广研

肾小管上皮衰老与肾衰

14:20-14:30

陈彪

衰弱防治策略

14:30-14:40

刘宝华

染色体稳态与老年疾病

14:40-14:50

刘光慧

基因编辑干预早老及衰老相关重大疾病

14:50-15:00

刘俊平

PD的研究进展

15:00-15:10

刘强

RNA稳态在引发老年相关疾病中的机制

15:10-15:20

宋默识

线粒体代谢问题在衰老中作用的研究进展

15:20-15:30

苏佳灿/苏笠

骨、关节老化损伤相关疾病的研究进展

15:30-15:40

王丽辉

慢阻肺的细胞衰老机制与分子靶点

15:40-15:50

王延江

AD的研究进展

15:50-16:00

All

Coffee break

16:00-16:10

杨泽

长寿遗传学

16:10-16:20

叶静

端粒、干细胞及老年相关疾病研究进展

16:20-16:30

张维绮

血管内皮衰老研究与血管衰老疾病的现状与未来

16:30-16:40

陈海云

1,25(OH)2D in the Prevention of   Mandibular Osteoporosis via the Deacetylase Sirtuin-1

16:40-16:50

司马健

Proteomics-based   target identification and translational study in aging-related diseases

16:50-17:00

孙传鑫

A Novel   Compound From Lycium barbarum Prevents from Bone Loss In Aging Mice

17:00-17:10

万懿琪

Genetic contribution to the escape of   centenarians from type-2 diabetes

17:10-17:20

吴嘉平

Potentiating   of exercise training with resveratrol during aging cardiac hypertrophy

17:20-17:30

周京军

Molecular   identities of intracellular calcium overload-induced injury in hearts

17:20-18:30

全体

晚餐（杭师大科技园B座佰家旺餐厅）、墙报浏览

2019年10月26日，星期六，杭州师范大学科技园

08:00-08:10

主席：刘俊平、申勇

致欢迎词

08:10-10:20

主席：申勇、周中军

主题2：衰老细胞的特征、命运调控（杭师大科技园E座3楼报告厅）

08:10-08:40

Suzanne Cory

BCL-2: from   translocation to therapy

08:40-09:00

冯新华

How Cancer   Escapes from TGF-βAnti-growth   Signaling

09:00-09:20

刘光慧

Using stem   cell and gene editing to study and treat aging-related disorders

09:20-09:40

孙宇

Senescence   associated secretory phenotype (SASP) in therapeutic resistance

09:40-10:00

肖智雄

IGF-1   transgenic mice exhibit aging-like phenotypes via SIRT1 axis

10:00-10:20

纪俊峰

CLDN1 as a   novel surface biomarker for targeted elimination of senescent cells

10:20-10:30

全体

茶歇、墙报浏览

10:30-12:40

主席：刘宝华、刘光慧

主题3：衰老和长寿的基因组机制（杭师大科技园E座3楼报告厅）

10:30-11:00

Jan Vilg

Single-cell   approaches in studying genome instability in aging

11:00-11:20

韩敬东

Heterogeneity of Human Aging

11:20-11:40

周中军

Lamin A-SIRT6-p53 axis in lifespan   control and aging

11:40-12:00

毛志勇

A PARP1-BRG1-SIRT1 axis promotes HR   repair at DNA damage sites

12:00-12:20

田小利

Epigenetic control of endothelial cell   senescence

12:20-12:40

王文恭

HuR调控肝脏脂质平衡

12:40-13:30

全体

合影留念、午餐（杭师大科技园B座佰家旺餐厅）、墙报浏览

13:00-13:30

王宏宇

基因工程小鼠在生物医学研究中的应用（E座3楼报告厅）

13:30-16:10

主席：宋默识、张维绮

主题4：激素、肥胖和心血管疾病（E座3楼报告厅）

13:30-13:50

John Funder

Adrenal hypertrophy and aldosterone adenoma in the elderly

13:50-14:10

洪登礼

Tracking down the Origin of Leukemic Stem Cell Programs in Fetal and   Aging Hematopoiesis Development

14:10-14:30

李卫

Eat   Yourself to Feed the Next Generation

14:30-14:50

刘宝华

Sirt7   regulates hepatic circadian phase coherence and gluconeogenesis

14:50-15:10

Helena Qin

Exploring   biased agonism for myocardial infarction

15:10-15:30

宋默识

Mitochondrial regulation of cardiac degeneration

15:30-15:50

张维绮

A Single-Cell   Transcriptomic Atlas of Arterial Aging in Cynomolgus Monkey

15:50-16:10

朱栩栋

Fine-Tuning   of PGC1α Regulates Cardiac Function and Longevity

16:10-16:20

全体

茶歇、墙报浏览

16:20-19:00

主席：刘强、申勇

主题5：神经退行性疾病的病理机制（E座3楼报告厅）

16:20-16:40

Nady Braidy

Promoting   Healthy Ageing: Unravelling the secrets of our cellular ‘energy sensor’ NAD⁺

16:40-17:00

蔡时青

Neural basis   of age-related behavioral deterioration

17:00-17:20

刘强

Epigenetic   regulation and Alzheimer's disease responses

17:20-17:40

佟超

Mitochondria   and neurodegeneration

17:40-18:00

刘磊

Enhancing   glycolysis attenuates Parkinson’s disease progression

18:00-18:20

王延江

From   pathogenesis to therapies for Alzheimer’s disease from systemic approaches

18:20-18:40

周嘉伟

Role of NG2   glia in neuroinflammation: Implication for Parkinson’s disease

18:40-19:00

Xinhua   Zhan

Bacterial   molecules associate with Alzheimer’s Disease neuropathology

19:00-20:30

全体

晚餐（杭师大科技园B座佰家旺餐厅）、墙报浏览

20:30-21:30

中国生物物理学会衰老生物学分会理事

衰老生物学分会理事会议（杭师大科技园D座6楼衰老所D618会议室）

2019年10月27日，星期日，杭州师范大学科技园

08:00-10:00

主席：陈畅、苏佳灿

主题   6: 代谢、炎症与骨关节退化疾病的研究进展（E座3楼报告厅）

08:00-08:20

陈畅

Redox-stress   Response Resistance (RRR) in Aging

08:20-08:40

罗剑

Regulation of   body length and osteoporosis by GPCRs

08:40-09:00

苗登顺

Sirt1   protects against estrogen deficiency-induced osteoporosis

09:00-09:20

苏佳灿

Central   problems and Countermeasures of osteoporotic fracture

09:20-09:40

许大康

Targeting inflammaging   and immune checkpoints for reversing immunosenescence

09:40-10:00

张晓玲

骨关节稳态失衡及退变调控

10:00-10:10

全体

茶歇、墙报浏览

10:10-12:20

主席：Eric Gilson、赵勇

主题7：端粒，DNA损伤反应与相关疾病（E座3楼报告厅）

10:10-10:40

Eric Gilson

TBA

10:40-11:00

鞠振宇

能量代谢和炎症与器官衰老

11:00-11:20

马文宾

Genome-wide   screens of telomerase associated proteins in live cells

11:20-11:40

赵勇

RBMX is   Required for Activation of ATR on Repetitive DNAs to Maintain Genome Stability

11:40-12:00

叶静

TERFA   controls neuronal homeostasis in zebrafishes

by regulating   glial cell functions

12:00-12:20

朱永群

Molecular   Mechanisms of Host Subversion by Bacterial Pathogens

12:20-13:00

全体

午餐（杭师大科技园B座佰家旺餐厅）、墙报浏览

13:00-15:10

主席：申勇、杨泽

主题8：衰老相关疾病的干预策略与方法（E座3楼报告厅）

13:00-13:30

Vincent Geli

The p21-mTert   knock-In mouse: a model of senescence bypass in lung disease

13:30-13:50

曲静

Gene therapy   alleviates osteoarthritis by preventing cellular senescence

13:50-14:10

Chris R   Triggle

Concentration-Dependent   effects of metformin on endothelial function

14:10-14:30

王峰

The function   of CST and its partner in resolving telomeric DNA replication problems

14:30-14:50

杨泽

Healthy   ageing and longevity

14:50-15:10

臧玉峰

Precise localization of abnormal   spontaneous brain activity by resting-state fMRI.

15:10-15:30  

全体

闭幕式并公布墙报获奖名单（E座3楼报告厅）